Measurement of Radioligand Binding by Scintillation Proximity Assay

  • Jenny Berry
  • Molly Price-Jones
Part of the Methods in Molecular Biology™ book series (MIMB, volume 306)


Scintillation proximity assay (SPA) is a homogeneous assay technology (1) which is bead-based and removes the need for a filtration step to separate bound from free ligand in a receptor-binding assay. The principle of the technology is shown in Fig. 1 .


Amersham Bioscience Assay Buffer Wheat Germ Agglutinin Soluble Receptor Copper Chelate 
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Copyright information

© Humana Press Inc. 2005

Authors and Affiliations

  • Jenny Berry
    • 1
  • Molly Price-Jones
    • 1
  1. 1.The Maynard Centre, GE Healthcare BiosciencesCardiffUK

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