Abstract
Cell-penetrating peptides (CPPs) have served as vehicles for the delivery of different molecules and particles into cells. The efficiency and noninvasive nature of peptide-mediated cellular transduction provides a promising tool for biomedical research. Studies of cell-penetrating constructs that deliver oligonucleotides, peptides, and proteins have elucidated several important cellular signaling mechanisms. Here we briefly describe the major classes of cell-penetrating peptides. We also present various strategies used to couple different cargoes to CPPs.
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Pooga, M., Langel, l. (2005). Synthesis of Cell-Penetrating Peptides for Cargo Delivery. In: Howl, J. (eds) Peptide Synthesis and Applications. Methods in Molecular Biology™, vol 298. Humana Press. https://doi.org/10.1385/1-59259-877-3:077
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DOI: https://doi.org/10.1385/1-59259-877-3:077
Publisher Name: Humana Press
Print ISBN: 978-1-58829-317-6
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