Summary
This chapter reviews the recent development in biological sensing using nanotechnologies based on carbon nanotubes and various nanowires. These 1D materials have shown unique properties that are efficient in interacting with biomolecules of similar dimensions, i.e., on a nanometer scale. Various aspects including synthesis, materials properties, device fabrication, biofunctionalization, and biological sensing applications of such materials are reviewed. The potential of such integrated nanobiosensors in providing ultrahigh sensitivity, fast response, and high-degree multiplex detection, yet with minimum sample requirements is demonstrated. This chapter is intended to provide comprehensive updated information for people from a variety of backgrounds but with common interests in the fast-moving interdisciplinary field of nanobiotechnology.
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Acknowledgments
We wish to thank Drs. M. Meyyappan, Jie Han, Alan Cassell, Wendy Fan, and Harry Partridge for encouragement and technical discussions during preparation of the manuscript. This work was supported by a NASA contract.
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Li, J., Ng, H.T., Chen, H. (2005). Carbon Nanotubes and Nanowires for Biological Sensing. In: Vo-Dinh, T. (eds) Protein Nanotechnology. Methods in Molecular Biology™, vol 300. Humana Press. https://doi.org/10.1385/1-59259-858-7:191
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