Abstract
Biochemical and functional analysis of poxvirus genomes, genes, and proteins has entered a new era with the recent sequencing of more than 30 poxvirus genomes. The management and analysis of this volume of sequence data in an efficient and effective manner requires specialized computer software. This chapter describes a number of bioinformatics techniques useful for analyzing poxvirus genomes. Some of the software discussed here have been developed by members of the Poxvirus Bioinformatics Resource Center (PBRC; funded by National Institutes of Health [NIH]) specifically for use with poxvirus genomes. These programs or, more accurately, suites of programs have many functions dedicated to poxvirus genome characterization. Significantly, this software has been designed with ease of use at a single location as the major goal.
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© 2004 Humana Press Inc., Totowa, NJ
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Upton, C. (2004). Poxvirus Bioinformatics. In: Isaacs, S.N. (eds) Vaccinia Virus and Poxvirology. Methods in Molecular Biology, vol 269. Humana Press. https://doi.org/10.1385/1-59259-789-0:347
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DOI: https://doi.org/10.1385/1-59259-789-0:347
Publisher Name: Humana Press
Print ISBN: 978-1-58829-229-2
Online ISBN: 978-1-59259-789-5
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