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Platelets and Megakaryocytes pp 323–345Cite as

Assays of Megakaryocyte Development

Cytoplasm, Storage Granules, and Demarcation Membranes

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Part of the book series: Methods In Molecular Biology™ ((MIMB,volume 272))

Abstract

Megakaryocytes (MKs), the bone-marrow precursors of platelets, are remarkable cells because of their rarity among hematopoietic cells, their exceptionally large size, and their polylobulated, polyploid nuclei. In order to accurately assay the precise stage of MK cytoplasmic differentiation, a large array of morphological techniques can be used, depending on the type of information required.

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Author information

Authors and Affiliations

  1. Départment d’Hématologie, Institut Cochin Paris, Service d’hématologie et d’immunologie, Faculté de Médecine Paris, Paris, France

    Arnaud Drouin & Elisabeth M. Cramer

  2. Départment d’Hématologie, Institut Cochin Paris, and Faculté de Médecine d’Amiens, Amiens, France

    Gulie Alimardani

Authors
  1. Arnaud Drouin
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  2. Gulie Alimardani
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  3. Elisabeth M. Cramer
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Editor information

Editors and Affiliations

  1. School of Animal and Microbial Sciences, The University of Reading, Reading, UK

    Jonathan M. Gibbins

  2. Department of Physiology, University of Cambridge, Cambridge, UK

    Martyn P. Mahaut-Smith

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© 2004 Humana Press Inc.

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Drouin, A., Alimardani, G., Cramer, E.M. (2004). Assays of Megakaryocyte Development. In: Gibbins, J.M., Mahaut-Smith, M.P. (eds) Platelets and Megakaryocytes. Methods In Molecular Biology™, vol 272. Humana Press. https://doi.org/10.1385/1-59259-782-3:323

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  • DOI: https://doi.org/10.1385/1-59259-782-3:323

  • Publisher Name: Humana Press

  • Print ISBN: 978-1-58829-101-1

  • Online ISBN: 978-1-59259-782-6

  • eBook Packages: Springer Protocols

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