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Platelet Microparticles

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Platelets and Megakaryocytes

Part of the book series: Methods In Molecular Biology™ ((MIMB,volume 272))

Abstract

One of the responses of activated platelets to certain stimuli is the shedding of microparticles. Microparticles released from platelets (PMPs) may play a role in the normal hemostatic response to vascular injury, as these particles exhibit prothrombinase activity (1). It is also possible that local generation of PMPs in small atherosclerotic arteries or arterioles may promote acute arterial occlusion by providing and expanding a catalytic surface for the coagulation cascade.

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Author information

Authors and Affiliations

  1. The First Department of Internal Medicine, Kansai Medical University, Osaka, Japan

    Shosaku Nomura

  2. The First Department of Internal Medicine, Kansai Medical School, Osaka, Japan

    Shirou Fukuhara

Authors
  1. Shosaku Nomura
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  2. Shirou Fukuhara
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Editor information

Editors and Affiliations

  1. School of Animal and Microbial Sciences, The University of Reading, Reading, UK

    Jonathan M. Gibbins

  2. Department of Physiology, University of Cambridge, Cambridge, UK

    Martyn P. Mahaut-Smith

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© 2004 Humana Press Inc.

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Nomura, S., Fukuhara, S. (2004). Platelet Microparticles. In: Gibbins, J.M., Mahaut-Smith, M.P. (eds) Platelets and Megakaryocytes. Methods In Molecular Biology™, vol 272. Humana Press. https://doi.org/10.1385/1-59259-782-3:269

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  • DOI: https://doi.org/10.1385/1-59259-782-3:269

  • Publisher Name: Humana Press

  • Print ISBN: 978-1-58829-101-1

  • Online ISBN: 978-1-59259-782-6

  • eBook Packages: Springer Protocols

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