Immunohistochemistry and In Situ Hybridization in Pancreatic Neoplasia

  • Robb E. Wilentz
  • Ayman Rahman
  • Pedram Argani
  • Christine Iacobuzio-Donahue
Part of the Methods in Molecular Medicine™ book series (MIMM, volume 103)


There are many types of pancreatic neoplasms. Pathologic examination, which includes both routine (e.g., hematoxylin-and-eosin staining) and ancillary (e.g., immunohistochemistry and in situ hybridization) techniques, is essential in correctly typing a pancreatic neoplasm. This chapter focuses on the use of immunohistochemistry and in situ hybridization in the differentiation of pancreatic neoplasms. The materials and methods of these two techniques are described in detail.

Key Words

Pancreatic cancer pancreas ductal adenocarcinoma immunohistochemistry in situ hybridization 


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Copyright information

© Humana Press Inc. 2005

Authors and Affiliations

  • Robb E. Wilentz
    • 1
  • Ayman Rahman
    • 1
  • Pedram Argani
    • 1
  • Christine Iacobuzio-Donahue
    • 1
  1. 1.Department of PathologyThe Johns Hopkins University School of MedicineBaltimore

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