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Using the TIGR Assembler in Shotgun Sequencing Projects

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Part of the Methods in Molecular Biology™ book series (MIMB, volume 255)

Abstract

The TIGR Assembler (TA) (1) is the sequence assembly program used in sequencing projects at The Institute for Genomic Research (TIGR). Development of the TA was based on the experience obtained in more than 20 sequencing projects completed at TIGR (see http://www.tigr.org). This extensive experience led to a sequence assembler that produces few misassemblies (2,3) and has been used successfully in whole-genome shotgun sequencing of prokaryotic and eukaryotic organisms, bacterial artificial chromosome-based sequencing of eukaryotic organisms, and expressed sequence tag assembly.

Keywords

Sequence Record Qual File Error File UNIX Command Input Sequence Data 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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Copyright information

© Humana Press Inc., Totowa, NJ 2004

Authors and Affiliations

  1. 1.The Institute for Genomic ResearchRockville

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