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Molecular and Cellular Approaches for Establishment of an In Vitro Spermatogenesis System

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Book cover Germ Cell Protocols

Part of the book series: Methods in Molecular Biology™ ((MIMB,volume 253))

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Abstract

Spermatogenesis is a complex, well-organized process including proliferation, differentiation, apoptosis, and morphogenesis through which differentiating daughter cells of spermatogonial stem cells develop into mature sperm (1,2). In men, this process requires approx 64 d, 52 d in the rat, and 35 d in the mouse. This process in mammals occurs in a highly coordinated fashion within the seminiferous epithelium inside the seminiferous tubule. Spermatogenesis can be divided into three phases.

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© 2004 Humana Press Inc., Totowa, NJ

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Nayernia, K., Engel, W. (2004). Molecular and Cellular Approaches for Establishment of an In Vitro Spermatogenesis System. In: Schatten, H. (eds) Germ Cell Protocols. Methods in Molecular Biology™, vol 253. Humana Press. https://doi.org/10.1385/1-59259-744-0:121

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  • DOI: https://doi.org/10.1385/1-59259-744-0:121

  • Publisher Name: Humana Press

  • Print ISBN: 978-1-58829-121-9

  • Online ISBN: 978-1-59259-744-4

  • eBook Packages: Springer Protocols

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