Abstract
The translocation of PKC to membranes has served as the hallmark for PKC activation since the historic discovery that phorbol esters cause PKC to redistribute from the cytosol to the membrane (1,2). In the 20 years since this discovery, the literature has been flooded with reports on the intracellular redistribution of PKC after agonist or phorbol ester stimulation (3). In recent years, this translocation has been beautifully captured in real time in live cells with the advent of fluorescent technologies (4,5).
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References
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© 2003 Humana Press Inc., Totowa, NJ
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Newton, A.C. (2003). Measuring the Interaction of Protein Kinase C with Membranes. In: Newton, A.C. (eds) Protein Kinase C Protocols. Methods in Molecular Biology™, vol 233. Humana Press. https://doi.org/10.1385/1-59259-397-6:89
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DOI: https://doi.org/10.1385/1-59259-397-6:89
Publisher Name: Humana Press
Print ISBN: 978-1-58829-068-7
Online ISBN: 978-1-59259-397-2
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