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Crystallization of the Protein Kinase Cδ C1B Domain

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Protein Kinase C Protocols

Part of the book series: Methods in Molecular Biology™ ((MIMB,volume 233))

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Abstract

The activation of conventional and novel protein kinase C (PKC) isozymes by diacylglycerol (DAG) and phorbol esters is mediated by their C1 domains (1–4. Several structures of PKC C1 domains have been determined using nuclear magnetic resonance (5–7) and X-ray crystallography (8).

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References

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Author information

Authors and Affiliations

  1. Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD

    Gongyi Zhang & James H. Hurley

Authors
  1. Gongyi Zhang
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  2. James H. Hurley
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Editor information

Editors and Affiliations

  1. Department of Pharmacology, University of California at San Diego, La Jolla, CA

    Alexandra C. Newton

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© 2003 Humana Press Inc., Totowa, NJ

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Zhang, G., Hurley, J.H. (2003). Crystallization of the Protein Kinase Cδ C1B Domain. In: Newton, A.C. (eds) Protein Kinase C Protocols. Methods in Molecular Biology™, vol 233. Humana Press. https://doi.org/10.1385/1-59259-397-6:299

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  • DOI: https://doi.org/10.1385/1-59259-397-6:299

  • Publisher Name: Humana Press

  • Print ISBN: 978-1-58829-068-7

  • Online ISBN: 978-1-59259-397-2

  • eBook Packages: Springer Protocols

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