Vallee, H. and Carré, H. (1904) Nature infectieuse de ľanemie de cheval. C. R. Acad. Sci.
Coffin, J. M., Huges, S. H., and Varmus, H. E. (1997) Retroviruses. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
Pereira, L. A., Bentley, K., Peeters, A., Churchill, M. J., and Deacon, N. J. (2000) A compilation of cellular transcription factor interactions with the HIV-1 LTR promoter. Nucleic Acids Res.
Freed, E. O. (1998) HIV-1 gag proteins: diverse functions in the virus life cycle. Virology
Li, X., Quan, Y., and Wainberg, M. A. (1997) Controlling elements in replication of the human immunodeficiency virus type 1. Cell Mol. Biol. (Noisy.-le-grand)
Wyatt, R. and Sodroski, J. (1998) The HIV-1 envelope glycoproteins: fusogens, antigens, and immunogens. Science
Kim, V. N., Mitrophanous, K., Kingsman, S. M., and Kingsman, A. J. (1998) Minimal requirement for a lentivirus vector based on human immunodeficiency virus type 1. J. Virol.
Chinnasamy, D., Chinnasamy, N., Enriquez, M. J., Otsu, M., Morgan, R. A., and Candotti, F. (2000) Lentiviral-mediated gene transfer into human lymphocytes: role of HIV-1 accessory proteins. Blood
Inubushi, R. and Adachi, A. (1999) Cell-dependent function of HIV-1 Vif for virus replication (Review). Int. J. Mol. Med.
Sheehy, A. M., Gaddis, N. C., Choi, J. O., and Malim, M. H. Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral VIF protein. Nature
Kafri, T., Blomer, U., Peterson, D. A., Gage, F. H., and Verma, I. M. (1997) Sustained expression of genes delivered directly into liver and muscle by lentiviral vectors. Nat. Genet.
Bukrinsky, M. and Adzhubei, A. (1999) Viral protein R of HIV-1. Rev. Med. Virol.
Elder, R. T., Benko, Z., and Zhao, Y. (2002) HIV-1 VPR modulates cell cycle G2/M transition through an alternative cellular mechanism other than the classic mitotic checkpoints. Front. Biosci.
Kappes, J. C. (1995) Viral protein x. Curr. Top. Microbiol. Immunol.
Connor, R. I., Chen, B. K., Choe, S., and Landau, N. R. (1995) Vpr is required for efficient replication of human immunodeficiency virus type-1 in mononuclear phagocytes. Virology
Mahalingam, S., Ayyavoo, V., Patel, M., Kieber-Emmons, T., and Weiner, D. B. (1997) Nuclear import, virion incorporation, and cell cycle arrest/differentiation are mediated by distinct functional domains of human immunodeficiency virus type 1 Vpr. J. Virol.
Eckstein, D. A., Sherman, M. P., Penn, M. L., et al. (2001) HIV-1 Vpr enhances viral burden by facilitating infection of tissue macrophages but not nondividing CD4+ T cells. J. Exp. Med.
De Noronha, C. M., Sherman, M. P., Lin, H. W., et al. (2001) Dynamic disruptions in nuclear envelope architecture and integrity induced by HIV-1 Vpr. Science
Jowett, J. B., Xie, Y. M., and Chen, I. S. (1999) The presence of human immuno-deficiency virus type 1 Vpr correlates with a decrease in the frequency of mutations in a plasmid shuttle vector. J. Virol.
Mansky, L. M. (1996) The mutation rate of human immunodeficiency virus type 1 is influenced by the vpr gene. Virology
Marcello, A., Zoppe, M., and Giacca, M. (2001) Multiple modes of transcriptional regulation by the HIV-1 Tat transactivator. IUBMB Life
Jones, K. A. (1997) Taking a new TAK on tat transactivation. Genes Dev.
Cujec, T. P., Cho, H., Maldonado, E., Meyer, J., Reinberg, D., and Peterlin, B. M. (1997) The human immunodeficiency virus transactivator Tat interacts with the RNA polymerase II holoenzyme. Mol. Cell Biol.
Benkirane, M., Chun, R. F., Xiao, H., et al. (1998) Activation of integrated provirus requires histone acetyltransferase. p300 and P/CAF are coactivators for HIV-1 Tat. J. Biol. Chem.
Roebuck, K. A., Rabbi, M. F., and Kagnoff, M. F. (1997) HIV-1 Tat protein can transactivate a heterologous TATAA element independent of viral promoter sequences and the transactivation response element. AIDS
de Parseval, A. and Elder, J. H. (1999) Demonstration that orf2 encodes the feline immunodeficiency virus transactivating (Tat) protein and characterization of a unique gene product with partial rev activity. J. Virol.
Purcell, D. F. and Martin, M. A. (1993) Alternative splicing of human immuno-deficiency virus type 1 mRNA modulates viral protein expression, replication, and infectivity. J. Virol.
Pollard, V. W. and Malim, M. H. (1998) The HIV-1 Rev protein. Annu. Rev. Microbiol.
Fukumori, T., Kagawa, S., Iida, S., et al. (1999) Rev-dependent expression of three species of HIV-1 mRNAs (review). Int. J. Mol. Med.
Yi, R., Bogerd, H. P., and Cullen, B. R. (2002) Recruitment of the Crm1 nuclear export factor is sufficient to induce cytoplasmic expression of incompletely spliced human immunodeficiency virus mRNAs. J. Virol.
Ruhl, M., Himmelspach, M., Bahr, G. M., et al. (1993) Eukaryotic initiation factor 5A is a cellular target of the human immunodeficiency virus type 1 Rev activation domain mediating trans-activation. J. Cell Biol.
Bogerd, H. P., Fridell, R. A., Madore, S., and Cullen, B. R. (1995) Identification of a novel cellular cofactor for the Rev/Rex class of retroviral regulatory proteins. Cell
Fritz, C. C., Zapp, M. L., and Green, M. R. (1995) A human nucleoporin-like protein that specifically interacts with HIV Rev. Nature
Reddy, T. R., Xu, W., Mau, J. K., et al. (1999) Inhibition of HIV replication by dominant negative mutants of Sam68, a functional homolog of HIV-1 Rev. Nat. Med.
Boris-Lawrie, K., Roberts, T. M., and Hull, S. (2001) Retroviral RNA elements integrate components of post-transcriptional gene expression. Life Sci.
Zolotukhin, A. S., Valentin, A., Pavlakis, G. N., and Felber, B. K. (1994) Continuous propagation of RRE(-) and Rev(-)RRE(-) human immunodeficiency virus type 1 molecular clones containing a cis-acting element of simian retrovirus type 1 in human peripheral blood lymphocytes. J. Virol.
Gasmi, M., Glynn, J., Jin, M. J., Jolly, D. J., Yee, J. K., and Chen, S. T. (1999) Requirements for efficient production and transduction of human immunodeficiency virus type 1-based vectors. J. Virol.
Bour, S. and Strebel, K. (2000) HIV accessory proteins: multifunctional components of a complex system. Adv. Pharmacol.
Geyer, M., Fackler, O. T., and Peterlin, B. M. (2001) Structure—function relationships in HIV-1 Nef. EMBO Rep.
Arold, S. T. and Baur, A. S. (2001) Dynamic Nef and Nef dynamics: how structure could explain the complex activities of this small HIV protein. Trends Biochem. Sci.
Chazal, N., Singer, G., Aiken, C., Hammarskjold, M. L., and Rekosh, D. (2001) Human immunodeficiency virus type 1 particles pseudotyped with envelope proteins that fuse at low pH no longer require Nef for optimal infectivity. J. Virol.
Clapham, P. R. and McKnight, A. (2001) HIV-1 receptors and cell tropism. Br. Med. Bull.
Jonckheere, H., Anne, J., and De Clercq, E. (2000) The HIV-1 reverse transcription (RT) process as target for RT inhibitors. Med. Res. Rev.
Gallay, P., Hope, T., Chin, D., and Trono, D. (1997) HIV-1 infection of nondividing cells through the recognition of integrase by the importin/karyopherin pathway. Proc. Natl. Acad. Sci. USA
Popov, S., Rexach, M., Ratner, L., Blobel, G., and Bukrinsky, M. (1998) Viral protein R regulates docking of the HIV-1 preintegration complex to the nuclear pore complex. J. Biol. Chem.
Jenkins, Y., McEntee, M., Weis, K., and Greene, W. C. (1998) Characterization of HIV-1 vpr nuclear import: analysis of signals and pathways. J. Cell Biol.
Haffar, O. K., Popov, S., Dubrovsky, L., et al. (2000) Two nuclear localization signals in the HIV-1 matrix protein regulate nuclear import of the HIV-1 pre-integration complex. J. Mol. Biol.
Zennou, V., Petit, C., Guetard, D., Nerhbass, U., Montagnier, L., and Charneau, P. (2000) HIV-1 genome nuclear import is mediated by a central DNA flap. Cell
Katzman, M. and Katz, R. A. (1999) Substrate recognition by retroviral integrases. Adv. Virus Res.
Kaplan, A. H. and Swanstrom, R. (1991) Human immunodeficiency virus type 1 gag proteins are processed in two cellular compartments. Proc. Natl. Acad. Sci. USA
Farson, D., Witt, R., McGuinness, R., et al. (2001) A new-generation stable inducible packaging cell line for lentiviral vectors. Hum. Gene Ther.
Xu, K., Ma, H., McCown, T. J., Verma, I. M., and Kafri, T. (2001) Generation of a stable cell line producing high-titer self-inactivating lentiviral vectors. Mol. Ther.
Seppen, J., Barry, S. C., Harder, B., and Osborne, W. R. (2001) Lentivirus administration to rat muscle provides efficient sustained expression of erythropoietin. Blood
Baek, S. C., Lin, Q., Robbins, P. B., Fan, H., and Khavari, P. A. (2001) Sustainable systemic delivery via a single injection of lentivirus into human skin tissue. Hum. Gene Ther.
Peng, K. W., Pham, L., Ye, H., et al. (2001) Organ distribution of gene expression after intravenous infusion of targeted and untargeted lentiviral vectors. Gene Ther.