Abstract
The value of early detection is clear from current tests for specific cancers: self-examination and mammography for breast, prostate-specific antigen (PSA) for prostate, and Pap smears for cervical cancers. No such method exists for early detection of lung cancer. New methods are being designed to test for the very few tumor cells released early in cancer progression into blood (or other body fluids). Single markers for specific cancers have been reported in blood samples or other accessible sites, but these vary between patients. We propose that sets of markers provide a reproducible general pattern, more certain for cancer detection. We have found a dozen markers present in 3 mL blood samples from cancer patients that are absent in blood samples from normal individuals (1,2).
Keywords
- Polymerase Chain Reaction
- Polymerase Chain Reaction Product
- Polymerase Chain Reaction Reaction
- Test Gene
- Differential Display
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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© 2003 Humana Press Inc., Totowa, NJ
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Fournier, M.V., Martin, K.J., Graner, E., Pardee, A.B. (2003). Sensitive Assays for Detection of Lung Cancer. In: Driscoll, B. (eds) Lung Cancer. Methods in Molecular Medicine™, vol 75. Humana Press, Totowa, NJ. https://doi.org/10.1385/1-59259-324-0:239
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DOI: https://doi.org/10.1385/1-59259-324-0:239
Publisher Name: Humana Press, Totowa, NJ
Print ISBN: 978-0-89603-920-9
Online ISBN: 978-1-59259-324-8
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