Abstract
The class II molecules of the human major histocompatibility complex are cell surface glycoproteins encoded by a series of genes located on the short arm of chromosome 6 in the HLA-D region. These molecules consist of an α and ß chain that associate as heterodimers on the surface of antigen presenting cells. They serve as receptors for processed peptides derived primarily from mem-brane and extracellular proteins that they present to CD4+ lymphocytes.
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Steiner, L.L., Moonsamy, P.V., Bugawan, T.L., Begovich, A.B. (2003). HLA-DPA1 and -DPB1 Typing Using the PCR and Nonradioactive Sequence-Specific Oligonucleotide Probes. In: Powis, S.H., Vaughan, R.W. (eds) MHC Protocols. Methods in Molecular Biology™, vol 210. Humana Press. https://doi.org/10.1385/1-59259-291-0:113
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DOI: https://doi.org/10.1385/1-59259-291-0:113
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