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Determination of Viral Infectivity

HSV, VZV, and CMV

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Antiviral Methods and Protocols

Part of the book series: Methods in Molecular Medicine™ ((MIMM,volume 24))

Abstract

Compared to the wide range of antibiotics that are available, the number of antiviral drugs is limited. However, herpesviruses have always been a major target for antiviral drug design, and there are a wide range of drugs at various stages of development. All of the assays described in this chapter provide relatively simple methods for plaque reduction assay of herpesviruses. Clearly, it is not possible to perform such assays on those herpesviruses that do not grow in adherent cells, such as Epstein-Barr virus. These require a different approach and are discussed elsewhere in this volume.

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References

  1. Welsh, M. D. (1991) Studies on the neutralisation of VZV by two specific monoclonal antibodies. Honours thesis, Queens University of Belfast, Belfast, UK.

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© 2000 Humana Press Inc.

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Harper, D.R. (2000). Determination of Viral Infectivity. In: Kinchington, D., Schinazi, R.F. (eds) Antiviral Methods and Protocols. Methods in Molecular Medicine™, vol 24. Humana Press. https://doi.org/10.1385/1-59259-245-7:119

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  • DOI: https://doi.org/10.1385/1-59259-245-7:119

  • Publisher Name: Humana Press

  • Print ISBN: 978-0-89603-561-4

  • Online ISBN: 978-1-59259-245-6

  • eBook Packages: Springer Protocols

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