Analysis of Bcr-Abl Function Using an In Vitro Embryonic Stem Cell Differentiation System

  • Takumi Era
  • Stephane Wong
  • Owen N. Witte
Part of the Methods in Molecular Biology™ book series (MIMB, volume 185)

Abstract

Numerous causative genes involved in human cancers, such as leukemias and lymphomas, have been identified (1). Considerable evidence has accumulated showing that disruptions of these genes can affect hematopoietic cell differentiation and growth. However, it remains largely unknown how these molecules function directly in hematopoietic stem cells.

Keywords

Differentiation Culture Medium Leukemia Inhibitory Factor Resuspend Cell Hematopoietic Development Liquid Nitrogen Tank 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Humana Press Inc., Totowa, NJ 2002

Authors and Affiliations

  • Takumi Era
    • 1
  • Stephane Wong
    • 1
  • Owen N. Witte
    • 1
  1. 1.Howard Hughes Medical InstituteUniversity of CaliforniaLos Angeles

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