Applications of Electron Microscopy for Studying Protein-DNA Complexes

  • Maria Schnos
  • Ross B. Inman
Part of the Methods in Molecular Biology™ book series (MIMB, volume 117)


Electron microscopic (EM) studies of DNA-protein complexes have led to many insights into biological reactions. There are three general methods that can be used to great advantage in such studies, each gives a different type of information, but each has its own disadvantages. In this chapter, we will discuss these methods and show examples of the usefulness of each.


Carbon Film Alcian Blue Direct Adsorption Electron Microscopic Grid Capillary Pipet 
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Copyright information

© Humana Press Inc. 1999

Authors and Affiliations

  • Maria Schnos
    • 1
  • Ross B. Inman
    • 1
  1. 1.Institute for Molecular VirologyUniversity of Wisconsin-MadisonMadison

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