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Fluorescent Detection of Telomerase Activity

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Telomeres and Telomerase

Part of the book series: Methods in Molecular Biology™ ((MIMB,volume 191))

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Abstract

Telomerase is now a significant factor in the fight against cancer and antiaging (1). It is becoming a valuable prognostic tool to determine if a particular tissue is likely to develop cancer (2). The ability to detect telomerase activity in patients with cancer has also been correlated with clinical staging of some tumors (3-7). The regulation of telomerase and the ability to inhibit the enzyme is also an important aspect in future drug development for both anticancer and antiaging purposes (8-11). Thus, the most sensitive and accurate methods are needed to detect telomerase in various sample formats.

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© 2002 Humana Press Inc., Totowa, NJ

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Aldous, W.K., Marean, A.J., DeHart, M.J., Moore, K.H. (2002). Fluorescent Detection of Telomerase Activity. In: Double, J.A., Thompson, M.J. (eds) Telomeres and Telomerase. Methods in Molecular Biology™, vol 191. Humana Press. https://doi.org/10.1385/1-59259-189-2:137

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  • DOI: https://doi.org/10.1385/1-59259-189-2:137

  • Publisher Name: Humana Press

  • Print ISBN: 978-0-89603-657-4

  • Online ISBN: 978-1-59259-189-3

  • eBook Packages: Springer Protocols

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