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Case Study of QTL Analysis in a Mouse Model of Asthma

  • Protocol
Book cover Quantitative Trait Loci

Part of the book series: Methods in Molecular Biology™ ((MIMB,volume 195))

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Abstract

Asthma is the most common childhood disease (1). It is characterized by inflammation of the small airways of the lung that produces intermittent narrowing of the respiratory bronchioles, airflow limitation, and the symptoms of wheezing, chest tightness, and breathless ness. The most common form is allergic asthma, also known as atopic asthma. The atopic state is distinguished by the strength of the immunoglobulin E (IgE) response to commonly inhaled proteins, known as allergens.

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Author information

Authors and Affiliations

  1. Asthma Genetics, The Wellcome Trust Centre for Human Genetics, University of Oxford, UK

    Youming Zhang

  2. Asthma Genetics, The Wellcome Trust Centre for Human Genetics, University of Oxford, UK

    William Cookson

Authors
  1. Youming Zhang
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  2. William Cookson
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Editor information

Editors and Affiliations

  1. Genetic Epidemiology, Department of Medical Informatics, University of Utah School of Medicine, Salt Lake City, UT

    Nicola J. Camp

  2. Institute for Cancer Studies, University of Sheffield Medical School, Sheffield, UK

    Angela Cox

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© 2002 Humana Press Inc.

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Zhang, Y., Cookson, W. (2002). Case Study of QTL Analysis in a Mouse Model of Asthma. In: Camp, N.J., Cox, A. (eds) Quantitative Trait Loci. Methods in Molecular Biology™, vol 195. Humana Press. https://doi.org/10.1385/1-59259-176-0:253

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  • DOI: https://doi.org/10.1385/1-59259-176-0:253

  • Publisher Name: Humana Press

  • Print ISBN: 978-0-89603-927-8

  • Online ISBN: 978-1-59259-176-3

  • eBook Packages: Springer Protocols

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