Abstract
The recognition of cancer as a genetic disease has changed the approach investigators take to understanding the mechanisms of carcinogenesis. The discovery of oncogenes, and the recognition of the inactivation of tumor suppressor genes, DNA repair enzymes, and of apoptotic pathways have provided a clearer picture of the dysregulation which is required for a cell to become a cancer.
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Worthington, M.T., Luo, R.Q. (2001). Transfection Assays for Transformation of Model Colonic Cell Lines. In: M., S. (eds) Colorectal Cancer. Methods in Molecular Medicine, vol 50. Humana Press. https://doi.org/10.1385/1-59259-084-5:259
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DOI: https://doi.org/10.1385/1-59259-084-5:259
Publisher Name: Humana Press
Print ISBN: 978-0-89603-767-0
Online ISBN: 978-1-59259-084-1
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