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The Molecular Pathogenesis of Ovarian Cancer

  • Protocol
Ovarian Cancer

Part of the book series: Methods in Molecular Medicine™ ((MIMM,volume 39))

Abstract

In recent years, there has been considerable progress in understanding the molecular events that give rise to clonal tumor development. This is best described by the steps in the development of colorectal tumors in which the activation of cellular protooncogenes and inactivation of several tumor suppressor genes has been elucidated (1). The well- defined steps in the development of these tumors from normal epithelium through adenomas or benign tumors to carcinomas has now been paralleled by identification of several genetic loci which are mutated as the tumor develops.

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  1. S. E. Hilary Russell
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  1. Department of Surgery, University of Glasgow, Glasgow, Scotland

    John M. S. Bartlett

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© 2000 Humana Press Inc.

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Hilary Russell, S.E. (2000). The Molecular Pathogenesis of Ovarian Cancer. In: Bartlett, J.M.S. (eds) Ovarian Cancer. Methods in Molecular Medicine™, vol 39. Humana Press. https://doi.org/10.1385/1-59259-071-3:25

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  • DOI: https://doi.org/10.1385/1-59259-071-3:25

  • Publisher Name: Humana Press

  • Print ISBN: 978-0-89603-583-6

  • Online ISBN: 978-1-59259-071-1

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