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Preparation of Cell-Wall Fractions from Mycobacteria

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Mycobacteria Protocols

Part of the book series: Methods in Molecular Biology™ ((MIMB,volume 101))

Abstract

Research extending over 50 years has implicated various components of the mycobacterial cell-wall matrix in many host responses associated with tuberculosis and other mycobacterioses (1). The observed responses originally included granuloma formation, high-titer IgG antibodies, and the state of the T cell-mediated immunological anergy evident in multibacillary leprosy and, more recently, in the induction of specific cytokines, phagocytosis of the organism, cellular refractivity to cytokine stimulation, and regulation of phagosome-lysosome fusion.

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Authors
  1. Gurdyal S. Besra
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Editors and Affiliations

  1. London School of Hygiene and Tropical Medicine, London, UK

    Tanya Parish  & Neil G. Stoker  & 

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© 1998 Humana Press Inc., Totowa, NJ

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Besra, G.S. (1998). Preparation of Cell-Wall Fractions from Mycobacteria. In: Parish, T., Stoker, N.G. (eds) Mycobacteria Protocols. Methods in Molecular Biology™, vol 101. Humana Press. https://doi.org/10.1385/0-89603-471-2:91

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  • DOI: https://doi.org/10.1385/0-89603-471-2:91

  • Publisher Name: Humana Press

  • Print ISBN: 978-0-89603-471-6

  • Online ISBN: 978-1-59259-576-1

  • eBook Packages: Springer Protocols

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