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Apoptosis Techniques and Protocols pp 161–182Cite as

Both Irreversible Neuronal Death and Reversible Neuronal Stress Are Associated with Increased Levels of Statin, a Marker of Cell Cycle Arrest

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Part of the book series: Neuromethods ((NM,volume 29))

Abstract

It is well known that cell death forms an important part of normal developmental and plastic processes in the brain. For example, during development, proliferating neuronal precursors generate a population of differentiated neurons, some of which make contact with their targets and survive. Neurons that cannot make appropriate targets activate an endogenous gene-directed death program (Cunningham, 1982; Oppenheimer, 1991). Thus, there is an important relationship between cell proliferation, differentiation, and death in neurons.

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Authors and Affiliations

  1. Douglas Hospztal Research Centre, Centre for Studies on Aging, Departments of Psychiatry and Medzcine, McGill University, Montréal, Canada

    Patricia Boksa, Uwe Beffert, Doris Dea, Richard Alonso, Dayan O’Donnell & Judes Poirier

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  1. Patricia Boksa
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  2. Uwe Beffert
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  3. Doris Dea
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  4. Richard Alonso
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  5. Dayan O’Donnell
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Editors and Affiliations

  1. Douglas Hospital Research Centre, Verdun, Canada

    Judes Poirier

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© 1997 Humana Press Inc.

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Boksa, P., Beffert, U., Dea, D., Alonso, R., O’Donnell, D., Poirier, J. (1997). Both Irreversible Neuronal Death and Reversible Neuronal Stress Are Associated with Increased Levels of Statin, a Marker of Cell Cycle Arrest. In: Poirier, J. (eds) Apoptosis Techniques and Protocols. Neuromethods, vol 29. Humana Press. https://doi.org/10.1385/0-89603-451-8:161

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  • DOI: https://doi.org/10.1385/0-89603-451-8:161

  • Publisher Name: Humana Press

  • Print ISBN: 978-0-89603-451-8

  • Online ISBN: 978-1-59259-634-8

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