Abstract
Epitope libraries provide an extremely efficient means for epitope mapping and the development of novel diagnostic markers. Filamentous phage fd-tet expression systems have been developed in order to construct such libraries containing tens to hundreds of mlllions of random peptlde sequences that can be screened for their abihty to bind particular antibodies (1). In essence these phage-expressed peptides mimic the determinants of the antigen that are recognized by the antibodies.
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© 1998 Humana Press Inc., Totowa, NJ
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Stern, B., Gershoni, J.M. (1998). Construction and Use of a 20-mer Phage Display Epitope Library. In: Cabilly, S. (eds) Combinatorial Peptide Library Protocols. Methods in Molecular Biology™, vol 87. Humana Press. https://doi.org/10.1385/0-89603-392-9:137
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DOI: https://doi.org/10.1385/0-89603-392-9:137
Publisher Name: Humana Press
Print ISBN: 978-0-89603-392-4
Online ISBN: 978-1-59259-571-6
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