Abstract
The role of mucus in the protection of intestinal, bronchial, nasopharyngeal, and cervical mucosae has long been recognized, but poorly understood. Research has been stimulated by the expectation that an underlying mucus abnormality might be present, not only in diseases such as cystic fibrosis where there is an obvious physical alteration in mucus, but also in conditions such as inflammatory bowel disease, peptic ulceration, and intestinal cancer where mucus abnormalities at present seem more subtle (1). Progress has been relatively slow, however, not least because of the difficulties in obtaining a pure but undamaged mucus glycoprotein (mucin) preparation.
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References
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© 1998 Humana Press Inc., Totowa, NJ
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Campbell, B.J., Rhodes, J.M. (1998). Purification of Gastrointestinal Mucins and Analysis of Their O-Linked Oligosaccharides. In: Hounsell, E.F. (eds) Glycoanalysis Protocols. Methods in Molecular Biology™, vol 76. Humana Press. https://doi.org/10.1385/0-89603-355-4:161
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DOI: https://doi.org/10.1385/0-89603-355-4:161
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