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The Use of Databases in Searching the Literature of Biological Mass Spectrometry

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Book cover Protein and Peptide Analysis by Mass Spectrometry

Part of the book series: Methods in Molecular Biology™ ((MIMB,volume 61))

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Abstract

Now that mass spectrometric techniques can be applied to a much wider range of molecules, the problem of searching the literature in order to find out whether or not the mass spectrum of a particular analyte has been reported has increased significantly. For example, many reports of mass spectral data now may be found in journals with which the mass spectrometrist is almost certainly unfamiliar. In this connection, it might be thought that the ready availability of a number of computerized bibliographic databases would mean that this problem can easily be solved by using the most appropriate database. The purpose of the present chapter is to show, by means of a detailed consideration of the reporting of a key biochemical analyte, human hemoglobin, that this is not the case, since a number of key references are overlooked. The reasons for this finding, which confirm previous Salford studies on the efficiency of literature databases for small molecules (1,2), are first that none of the databases cover 100% of the scientific literature and, second, no system is 100% efficient in its abstracting of experimental measurements published in scientific papers. The reason for the choice of human hemoglobin to illustrate this data searching problem is that one of us had conducted joint research with the late Professor M. Barber on the measurement of the mass spectra of intact globins using fast-atom bombardment-mass spectrometry techniques (3), and this research interest is still maintained by the first author (4).

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Appendix

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Authors and Affiliations

  1. Biological Materials Analysis Research Unit, University of Salford, Salford, UK

    Ronald W. A. Oliver

  2. Academic Information Services, University of Salford, Salford, UK

    Michael P. Carrier

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  1. Ronald W. A. Oliver
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  1. Manchester, UK

    John R. Chapman

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Oliver, R.W.A., Carrier, M.P. (1996). The Use of Databases in Searching the Literature of Biological Mass Spectrometry. In: Chapman, J.R. (eds) Protein and Peptide Analysis by Mass Spectrometry. Methods in Molecular Biology™, vol 61. Humana Press. https://doi.org/10.1385/0-89603-345-7:295

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  • DOI: https://doi.org/10.1385/0-89603-345-7:295

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  • Print ISBN: 978-0-89603-345-0

  • Online ISBN: 978-1-59259-547-1

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