Abstract
The ability to detect low numbers of DNA target sequences has been greatly enhanced by the development of geometric amplification techniques, most of which employ enzymatic methods to replicate a target DNA or RNA sequence in an autocatalytic fashion. These techniques have become so widely used that a new journal, PCR Methods and Applications, has arisen in an attempt to consolidate literature relevant to polymerase chain reactions (PCR) (1) and other amplification technologies.
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Shimer, G.H., Backman, K.C. (1995). Ligase Chain Reaction. In: Howard, J., Whitcombe, D.M. (eds) Diagnostic Bacteriology Protocols. Methods in Molecular Biology™, vol 46. Humana Press. https://doi.org/10.1385/0-89603-297-3:269
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DOI: https://doi.org/10.1385/0-89603-297-3:269
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