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Animal Models of the Wernicke-Korsakoff Syndrome

  • Maryse Héroux
  • Roger F. Butterworth
Protocol
Part of the Neuromethods book series (NM, volume 22)

Abstract

In humans, deficiency of thiamine (vitamin B,) is associated with two well-defined neurological disorders: a mixed sensorymotor neuropathy and the Wernicke-Korsakoff syndrome. Disturbances of thiamine metabolism may also play a role in other human diseases, such as infantile subacute necrotizing encephalomyelopathy (Leigh Disease), as well as in some forms of inherited ataxias. One of the characteristics of a number of these thiamine-deficiency disorders is the predilection to neuropathologic damage of specific regions of the central nervous system (CNS).

Keywords

Inferior Colliculus Vestibular Nucleus Thiamine Deficiency Mammillary Body Medial Vestibular Nucleus 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© The Humana Press Inc 1992

Authors and Affiliations

  • Maryse Héroux
    • 1
  • Roger F. Butterworth
    • 1
  1. 1.Laboratory of NeurochemistryUniversity of MontrealMontrealCanada

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