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Animal Models for Reye’s Syndrome

  • M. G. Murphy
  • S. C. Digout
  • J. F. S. Crocker
Part of the Neuromethods book series (NM, volume 22)

Abstract

Reye’s Syndrome (RS) was first documented by Douglas Reye and colleagues in 1963 as an “encephalopathy with fatty degeneration of the viscera,” a rare entity, but one that at that time was associated with an 80% mortality rate (Reye et al., 1963). Although the apparent incidence and outcome of the disease have improved, it continues to be one of the major causes of noninflammatory neurologic death after a viral illness in children (Sullivan-Boylai and Corey, 1981; Heubi et al., 1987).

Keywords

Octanoic Acid Viral Illness Serum Free Fatty Acid Serum Glutamic Oxaloacetic Transaminase Carbamyl Phosphate 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© The Humana Press Inc 1992

Authors and Affiliations

  • M. G. Murphy
    • 1
  • S. C. Digout
    • 2
  • J. F. S. Crocker
    • 2
  1. 1.Department of Physiology and BiophysicsDalhousie UniversityHalifaxCanada
  2. 2.Department ofPediatricsDalhousie UniversityHalifaxCanada

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