Abstract
Epstein-Barr virus (EBV) is able to immortalize human B-lymphocytes with high efficiency. This property underlies the role of EBV in a number of human diseases. First, EBV is the causative agent of infectious mononucleosis, which is a benign proliferation of B-lymphocytes (1). Second, EBV is involved in the etiology of Burkitt’s lymphoma (2) and of invasive B-lymphocyte proliferations found in immunosuppressed individuals (3).
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© 1991 The Humana Press Inc., Clifton, NJ
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Brickell, P.M. (1991). Immortalization of Human B-Lymphocytes by Epstein-Barr Virus. In: Collins, M.K.L. (eds) Practical Molecular Virology. Methods in Molecular Biology, vol 8. Humana Press. https://doi.org/10.1385/0-89603-191-8:213
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DOI: https://doi.org/10.1385/0-89603-191-8:213
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