Protein Phosphatase Protocols

Volume 365 of the series Methods in Molecular Biology pp 9-22

A Brief Introduction to the Protein Phosphatase Families

  • Tomas MustelinAffiliated withThe Burnham Institute

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This chapter introduces the main families of protein phosphatases encoded by the human genome and discusses their classification, overall structure, regulation, and physiological functions in human health and diseases. The topics of redundancy, diversity, and dynamic expression in individual cell types are briefly introduced, and the importance of technological approaches to phosphatase research is emphasized.

Key Words

Protein phosphatases PTPs, DSPs HAD family drug targets