The combination of nanotechnology and molecular biology has led to a new generation of nanoscale-based devices and methods for probing the cell machinery and elucidating intimate life processes occurring at the molecular level that were heretofore invisible to human inquiry. This chapter provides a brief overview of the field of nanotechnology and its applications to the study, design, and use of protein systems in biology and medicine.
Key WordsNanotechnology protein nanosensor nanoprobe DNA RNA molecular motor
- 1.Feynman, R. (1960) There’s plenty of room at the bottom: an invitation to enter a new field of physics. Eng. Sci. February Issue.Google Scholar
- 2.Drexler, E. K. (1986) Engines of Creation, Anchor Books, New York.Google Scholar
- 3.Cosman, M., Lightstone, F. C., Krishnan, V. V., Zeller, L., Prieto, M. C., Roe, D. C., and Balhorn, R. (2002) Screening mixtures of small molecules for binding to multiple sites on the surface of tetanus toxin C fragment by bioaffinity NMR. Chem. Res. Toxicol. 15, 1218–1228.PubMedCrossRefGoogle Scholar
- 6.Vo-Dinh, T. (ed.) (2003) Biomedical Photonics Handbook, CRC Press, Boca Raton, FL.Google Scholar
- 11.Vo-Dinh, T. (2003) Nanosensors: probing the sanctuary of individual living cells. J. Cell. Biochem. 39(Suppl.), 154–161.Google Scholar