DNA Arrays

Volume 170 of the series Methods in Molecular Biology™ pp 103-116

Automated Genotyping Using the DNA MassArray™ Technology

  • Christian JurinkeAffiliated withSEQUENOM GmbH
  • , Dirk van den BoomAffiliated withSEQUENOM GmbH
  • , Charles R. CantorAffiliated withSEQUENOM Inc.
  • , Hubert KösterAffiliated withSEQUENOM Inc.

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The ongoing progress in establishing a reference sequence as part of the Human Genome Project (1) has revealed a new challenge: the large-scale identification and detection of intraspecies sequence variations, either between individuals or populations. The information drawn from those studies will lead to a detailed understanding of genetic and environmental contributions to the etiology of complex diseases.