Transgenesis Techniques pp 305-341

Part of the Methods in Molecular Biology book series (MIMB, volume 180)

Analysis of Transgenic Mice

  • Stefan Selbert
  • Dominic Rannie

Abstract

The first step in the analysis of potentially transgenic mice is the characterizaton of their altered genotype. A strategy must be devised that allows easy and reliable discrimination between wild-type animals and those carrying additional transgenes or introduced targeted mutations. It is also necessary to demonstrate that the characteristics of the alteration are as desired.

Copyright information

© Humana Press Inc. 2002

Authors and Affiliations

  • Stefan Selbert
    • 1
  • Dominic Rannie
    • 2
  1. 1.Mice and More GmbH and Co.HamburgGermany
  2. 2.Department of PathologyUniversity of Edinburgh Medical SchoolEdinburghUK

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