Analysis of Transgenic Mice

  • Stefan Selbert
  • Dominic Rannie
Part of the Methods in Molecular Biology book series (MIMB, volume 180)

Abstract

The first step in the analysis of potentially transgenic mice is the characterizaton of their altered genotype. A strategy must be devised that allows easy and reliable discrimination between wild-type animals and those carrying additional transgenes or introduced targeted mutations. It is also necessary to demonstrate that the characteristics of the alteration are as desired.

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Copyright information

© Humana Press Inc. 2002

Authors and Affiliations

  • Stefan Selbert
    • 1
  • Dominic Rannie
    • 2
  1. 1.Mice and More GmbH and Co.HamburgGermany
  2. 2.Department of PathologyUniversity of Edinburgh Medical SchoolEdinburghUK

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