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Antibody Production

  • Robert Burns
Protocol
  • 127 Downloads
Part of the Springer Protocols Handbooks book series (SPH)

Abstract

Antibodies are proteins that are produced by the immune systems of animals in response to foreign substances. The immune system has the ability to recognize material as nonself or foreign and mount a response to them. Substances that elicit this are known as immunogens or antigens, and one of the outcomes of the immune response is the production of antibodies that will recognize and bind to the eliciting substance.

Keywords

Ascitic Fluid Myeloma Cell Line Antibody Molecule Needlestick Injury Donor Animal 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

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    Kennet, R. H., Denis, K. A., Tung, A. S., and Klinman, N. R. (1978) Hybrid plasmacytoma production: fusions with adult spleen cells, monoclonal spleen fragments, neonatal spleen cells and human spleen cells. Curr. Top. Microbiol. Immunol. 81, 485. Google Scholar
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    Kohler, G. and Milstein, C. (1975) Continuous cultures of fused cells secreting antibody of predefined specificity. Nature 256, 495–497.PubMedCrossRefGoogle Scholar
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    Harlow, E. and Lane, D. (1988) Antibodies: A Laboratory Manual, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, pp. 96–97.Google Scholar
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    Kemeny, D. M. and Chandler, S. (1988) ELISA and Other Solid Phase Immunoassays, John Wiley & Sons, pp. 1–29.Google Scholar

Copyright information

© Humana Press Inc., Totowa, NJ 2002

Authors and Affiliations

  • Robert Burns
    • 1
  1. 1.Antibody UnitScottish Agricultural Science AgencyEdinburghUK

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