Antibody Production

  • Robert Burns
Part of the Springer Protocols Handbooks book series (SPH)


Antibodies are proteins that are produced by the immune systems of animals in response to foreign substances. The immune system has the ability to recognize material as nonself or foreign and mount a response to them. Substances that elicit this are known as immunogens or antigens, and one of the outcomes of the immune response is the production of antibodies that will recognize and bind to the eliciting substance.


Ascitic Fluid Myeloma Cell Line Antibody Molecule Needlestick Injury Donor Animal 
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  1. 1.
    Roitt, I., Brostoff, J., and Male, D. (1996) Immunology, C. V. Mosby, St. Louis, pp. 1.7–1.8.Google Scholar
  2. 2.
    Kennet, R. H., Denis, K. A., Tung, A. S., and Klinman, N. R. (1978) Hybrid plasmacytoma production: fusions with adult spleen cells, monoclonal spleen fragments, neonatal spleen cells and human spleen cells. Curr. Top. Microbiol. Immunol. 81, 485. Google Scholar
  3. 3.
    Kohler, G. and Milstein, C. (1975) Continuous cultures of fused cells secreting antibody of predefined specificity. Nature 256, 495–497.PubMedCrossRefGoogle Scholar
  4. 4.
    Harlow, E. and Lane, D. (1988) Antibodies: A Laboratory Manual, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, pp. 96–97.Google Scholar
  5. 5.
    Kemeny, D. M. and Chandler, S. (1988) ELISA and Other Solid Phase Immunoassays, John Wiley & Sons, pp. 1–29.Google Scholar

Copyright information

© Humana Press Inc., Totowa, NJ 2002

Authors and Affiliations

  • Robert Burns
    • 1
  1. 1.Antibody UnitScottish Agricultural Science AgencyEdinburghUK

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