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Herpes Simplex Virus Life Cycle and the Design of Viral Vectors

  • David S. Latchman
Part of the Methods in Molecular Biology book series (MIMB, volume 8)

Abstract

Herpes simplex viruses types 1 and 2 (HSV-1 and HSV-2) are doublestranded DNA viruses with a genome size of 152 kbp. The genome consists of two unique regions, UL (long) and Us (short), flanked by repeated sequences (Fig. 1; for review, see ref. 1). The two viruses are closely related, and both infect humans, producing mucocutaneous sores that are predominantly facial in the case of HSV-1 and genital in the case of HSV-2.

Keywords

Viral Genome Herpes Simplex Virus Type Thymidine Kinase Recombinant Virus Chloramphenicol Acetyl Transferase 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© The Humana Press Inc., Clifton, NJ 1991

Authors and Affiliations

  • David S. Latchman
    • 1
  1. 1.Medical Molecular Biology UnitUniversity College and Middlesex School of MedicineLondonUK

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