Abstract
Opioid receptors are members of the G-protein coupled receptor (GPCR) family characterized by the presence of seven transmembrane domains. These receptors are classified as mu (μ), delta (δ), and kappa (κ). Activation of these receptors leads to uncoupling of the inhibitory G-proteins (Gi) followed by the activation of multiple signal transduction pathways including the inhibition of adenylyl cyclase, modulation of inwardly rectifying K+ channels or voltage-dependent calcium channels and regulation of mitogen-activated protein (MAP) kinase activity (1–4).
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© 2003 Humana Press Inc.
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Gomes, I., Devi, L.A., Filipovska, J. (2003). Opioid Receptor Oligomerization. In: Pan, Z.Z. (eds) Opioid Research. Methods in Molecular Biology™, vol 84. Humana Press. https://doi.org/10.1385/1-59259-379-8:157
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DOI: https://doi.org/10.1385/1-59259-379-8:157
Publisher Name: Humana Press
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