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miRNomics: MicroRNA Biology and Computational Analysis pp 243–256Cite as

Computational Prediction of MicroRNA Function and Activity

Part of the Methods in Molecular Biology book series (MIMB,volume 1107)

Abstract

Inferring microRNA (miRNA) functions and activities has been extremely important to understand their system-level roles and the mechanisms behind the cellular behaviors of their target genes. This chapter first details methodologies necessary for prediction of function and activity. It then introduces the computational methods available for investigation of sequence and experimental data and for analysis of the information flow mediated through miRNAs.

Keywords

  • Regulatory networks
  • Transcriptional modules
  • Biclustering
  • Bipartite graphs
  • Multiway analysis

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  • DOI: 10.1007/978-1-62703-748-8_15
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Acknowledgement

This study was supported by the Scientific and Technological Research Council of Turkey (TUBITAK) under the Project 110E160.

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Authors and Affiliations

  1. Department of Computer Engineering, Baskent University, Ankara, Turkey

    Hasan Oğul

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  1. Hasan Oğul
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Editor information

Editors and Affiliations

  1. Dabburiya Village, Israel

    Malik Yousef

  2. Izmir Institute of Technology, Izmir, Turkey

    Jens Allmer

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Oğul, H. (2014). Computational Prediction of MicroRNA Function and Activity. In: Yousef, M., Allmer, J. (eds) miRNomics: MicroRNA Biology and Computational Analysis. Methods in Molecular Biology, vol 1107. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-62703-748-8_15

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  • DOI: https://doi.org/10.1007/978-1-62703-748-8_15

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