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The Pathway of miRNA Maturation

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miRNA Maturation

Part of the book series: Methods in Molecular Biology ((MIMB,volume 1095))

Abstract

MicroRNAs (miRNAs) are a novel class of 17–23 nucleotide short, nonprotein-coding RNA molecules which have emerged to be key players in posttranscriptional gene regulation. In this chapter we give an in-depth review of the classic, canonical mammalian miRNA maturation pathway and discuss new, noncanonical alternatives such as the mirtron pathway which were recently described.

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Authors and Affiliations

  1. Department of Dermatology, Venereology and Allergology, Ruhr-University Bochum, Bochum, Germany

    Michael Sand

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  1. Michael Sand
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Editors and Affiliations

  1. Institute for Chemistry, Humboldt Universität zu Berlin, Berlin, Berlin, Germany

    Christoph Arenz

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Sand, M. (2014). The Pathway of miRNA Maturation. In: Arenz, C. (eds) miRNA Maturation. Methods in Molecular Biology, vol 1095. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-62703-703-7_1

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  • DOI: https://doi.org/10.1007/978-1-62703-703-7_1

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  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-62703-702-0

  • Online ISBN: 978-1-62703-703-7

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