Abstract
Gold nanoparticles have been a versatile tool in recent years for the exploration of biological systems. However, challenges with purification and adequate surface coverage limit the biocompatibility of gold nanoparticles. Here, we describe a detailed procedure for the synthesis, purification, and functionalization of biologically compatible gold nanoparticles for in vitro and in vivo studies.
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Acknowledgment
This work was supported by the NIH (GM077173 and EB014277).
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Moyano, D.F., Duncan, B., Rotello, V.M. (2013). Preparation of 2 nm Gold Nanoparticles for In Vitro and In Vivo Applications. In: Bergese, P., Hamad-Schifferli, K. (eds) Nanomaterial Interfaces in Biology. Methods in Molecular Biology, vol 1025. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-62703-462-3_1
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DOI: https://doi.org/10.1007/978-1-62703-462-3_1
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Publisher Name: Humana Press, Totowa, NJ
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