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Haemostasis pp 85–96Cite as

Reference Ranges of Coagulation Tests

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Part of the book series: Methods in Molecular Biology ((MIMB,volume 992))

Abstract

Reference ranges are a set of values that correctly include most of the subjects with characteristics similar to the reference group and exclude the others. When accurate, reference ranges aid physicians to interpret results of clinical measurements and thus establish diagnosis. However, obtaining accurate reference ranges is a very demanding procedure. This chapter provides basic definitions and theories as well as a step-by-step procedure for the analysis of reference values and determination of reference ranges of coagulation, focusing on quantitative clinical laboratory assays. Preanalytical and analytical factors as well as dependence on the age influencing reference values for coagulation assays and their transference are discussed.

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Author information

Authors and Affiliations

  1. Division of Haematology, University Children’s Hospital, Zurich, Switzerland

    Oliver Speer, Markus Schmugge, Claudia Metzger & Manuela Albisetti

Authors
  1. Oliver Speer
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  2. Markus Schmugge
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  3. Claudia Metzger
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  4. Manuela Albisetti
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Editor information

Editors and Affiliations

  1. Department of Paediatrics, University of Melbourne, n/a, Parkville, 3052, Victoria, Australia

    Paul Monagle

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© 2013 Humana Press

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Speer, O., Schmugge, M., Metzger, C., Albisetti, M. (2013). Reference Ranges of Coagulation Tests. In: Monagle, P. (eds) Haemostasis. Methods in Molecular Biology, vol 992. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-62703-339-8_6

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  • DOI: https://doi.org/10.1007/978-1-62703-339-8_6

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  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-62703-338-1

  • Online ISBN: 978-1-62703-339-8

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