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Present Technology and Future Trends in Point-of-Care Microfluidic Diagnostics

  • Lawrence KulinskyEmail author
  • Zahra Noroozi
  • Marc Madou
Protocol
Part of the Methods in Molecular Biology book series (MIMB, volume 949)

Abstract

This work reviews present technologies and developing trends in Point-of-Care (POC) microfluidic diagnostics platforms. First, various fluidics technologies such as pressure-driven flows, capillary flows, electromagnetically driven flows, centrifugal fluidics, acoustically driven flows, and droplet fluidics are categorized. Then three broad categories of POC microfluidic testing devices are considered: lateral flow devices, desktop and handheld POC diagnostic platforms, and emergent molecular diagnostic POC systems. Such evolving trends as miniaturization, multiplexing, networking, new more sensitive detection schemes, and the importance of sample processing are discussed. It is concluded that POC microfluidic diagnostics has a potential to improve patient treatment outcome and bring substantial savings in overall healthcare costs.

Key words

Point of care POC POCT Microfluidics Diagnostics Lateral flow Molecular diagnostics Immunoassay 

Notes

Acknowledgments

This work was supported by the National Science Foundation grants ECCS-0801792 and NIRT-0709085, National Institute of Health grant 1 R01 AIO89541-01, and UC Lab Fees Award 09-LR-09-117362 and sponsored by World Class University (WCU) program (R32-2008-000-20054-0) through the National Research Foundation of Korea funded by the Ministry of Education, Science and Technology.

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Copyright information

© Springer Science+Business Media,LLC 2013

Authors and Affiliations

  • Lawrence Kulinsky
    • 1
    Email author
  • Zahra Noroozi
    • 1
  • Marc Madou
    • 1
    • 2
    • 3
  1. 1.Department of Mechanical and Aerospace EngineeringUniversity of CaliforniaIrvineUSA
  2. 2.Department of Biomedical EngineeringUniversity of CaliforniaIrvineUSA
  3. 3.Ulsan National Institute of Science and Technology (UNIST)UlsanSouth Korea

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