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Cell Culture Assays to Evaluate Bacterial Toxicity and Virulence

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Part of the book series: Methods in Molecular Biology ((MIMB,volume 921))

Abstract

Helicobacter pylori CagA and VacA are two critical virulence factors that modulate disease severity in the infected host. The following chapter outlines methods employed to study the effects of these virulence factors on several key signaling pathways in epithelial cells.

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Acknowledgments

NLJ is supported by a Canadian Institute for Health Research operating grant (No. 17886).

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Correspondence to Nicola L. Jones .

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Raju, D., Rizzuti, D., Jones, N.L. (2012). Cell Culture Assays to Evaluate Bacterial Toxicity and Virulence. In: Houghton, J. (eds) Helicobacter Species. Methods in Molecular Biology, vol 921. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-62703-005-2_11

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  • DOI: https://doi.org/10.1007/978-1-62703-005-2_11

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  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-62703-004-5

  • Online ISBN: 978-1-62703-005-2

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