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Neurobehavioral Assessments of Spinal Cord Injury

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Animal Models of Acute Neurological Injuries II

Part of the book series: Springer Protocols Handbooks ((SPH))

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Abstract

Experimental spinal cord injuries can be categorized as being mild, moderate, or severe, based upon the extent of tissue damage and the severity of functional deficit incurred. The level of injury and unilateral or bilateral nature of an injury also greatly impact upon whether deficits involve single or multiple limbs. Having these features in mind, the investigator is directed towards performing the appropriate neurobehavioral tests to assess the functional capabilities of injured animals before and after therapeutic interventions have been applied. An ideal test should use quantitative methods that can provide some insight into the physiological mechanisms involved in functional recovery.

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Authors and Affiliations

  1. Department of Neurobiology and Anatomy, The Spinal Cord Research Center, Drexel University College of Medicine, Philadelphia, PA, USA

    Jed S. Shumsky & John D. Houlé

Authors
  1. Jed S. Shumsky
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  2. John D. Houlé
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Corresponding author

Correspondence to John D. Houlé .

Editor information

Editors and Affiliations

  1. School of Medicine, University of Pittsburgh, Terrace St. 3500, Pittsburgh, 15213, Pennsylvania, USA

    Jun Chen

  2. School of Medicine, Stark Neurosciences Res. Inst., Indiana University, W. Walnut St. 950, Indianapolis, 46202, Indiana, USA

    Xiao-Ming Xu

  3. School of Medicine, Department of Anatomy & Cell Biology, Indiana University, Barnhill Dr. 635, Indianapolis, 46202, Indiana, USA

    Zao C. Xu

  4. School of Medicine, Dept. Neurosurgery, Loma Linda University, Anderson St. 11234, Loma Linda, 92354, California, USA

    John H. Zhang

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Shumsky, J.S., Houlé, J.D. (2012). Neurobehavioral Assessments of Spinal Cord Injury. In: Chen, J., Xu, XM., Xu, Z., Zhang, J. (eds) Animal Models of Acute Neurological Injuries II. Springer Protocols Handbooks. Humana Press. https://doi.org/10.1007/978-1-61779-782-8_46

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  • DOI: https://doi.org/10.1007/978-1-61779-782-8_46

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  • Publisher Name: Humana Press

  • Print ISBN: 978-1-61779-781-1

  • Online ISBN: 978-1-61779-782-8

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