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Ovariectomy/Orchidectomy in Rodents

  • Aymen I. Idris
Protocol
Part of the Methods in Molecular Biology book series (MIMB, volume 816)

Abstract

This chapter describes the surgical procedures for ovariectomy and orchidectomy in mice and rats. In ­addition to providing technical details of the surgical techniques, details of anaesthesia and perioperative care are also included.

Key words

Surgery Ovariectomy Orchidectomy Oestrogen Androgen Rodents Mouse Rat Bone loss 

Notes

Acknowledgement

The author would like to thank Dr. Antonia Sophocleous PhD for providing the images for Figs. 1 and 2 and for critically reviewing the manuscript.

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Copyright information

© Springer Science+Business Media, LLC 2012

Authors and Affiliations

  1. 1.Bone and Cancer Group, Edinburgh Cancer Research UK Centre and Rheumatic Disease Unit, the Centre of Molecular MedicineUniversity of EdinburghEdinburghUK

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