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Biomedical Nanotechnology pp 179–185Cite as

Hydrogel Templates for the Fabrication of Homogeneous Polymer Microparticles

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Part of the book series: Methods in Molecular Biology ((MIMB,volume 726))

Abstract

Nano/microparticulate drug delivery systems with homogeneous size distribution and predefined shape are important in understanding the influence of the geometry and dimensions of these systems on blood circulation times and cellular uptake. We present a general method using water dissolvable hydrogel templates for the fabrication of homogeneous, shape-specific polymer/drug constructs in the size range of 200 nm to 50 μm. This hydrogel template strategy is mild, inexpensive, and readily scalable for the fabrication of multifunctional drug delivery vehicles.

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Acknowledgment

This project was supported in part by the Showalter Trust Fund from Purdue Research Foundation.

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Authors and Affiliations

  1. Departments of Biomedical Engineering and Pharmaceutics, Purdue University, West Lafayette, IN, USA

    Kinam Park

  2. Akina Inc., West Lafayette, IN, USA

    Kinam Park

Authors
  1. Ghanashyam Acharya
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  2. Matthew McDermott
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  3. Soo Jung Shin
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  4. Haesun Park
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  5. Kinam Park
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Corresponding author

Correspondence to Kinam Park .

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Editors and Affiliations

  1. Center for Nanoscale Materials, Argonne National Laboratory, S. Cass Avenue 9700, Argonne, 60439, Illinois, USA

    Sarah J. Hurst

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Acharya, G., McDermott, M., Shin, S.J., Park, H., Park, K. (2011). Hydrogel Templates for the Fabrication of Homogeneous Polymer Microparticles. In: Hurst, S. (eds) Biomedical Nanotechnology. Methods in Molecular Biology, vol 726. Humana Press. https://doi.org/10.1007/978-1-61779-052-2_12

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  • DOI: https://doi.org/10.1007/978-1-61779-052-2_12

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  • Publisher Name: Humana Press

  • Print ISBN: 978-1-61779-051-5

  • Online ISBN: 978-1-61779-052-2

  • eBook Packages: Springer Protocols

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