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In Vitro Adult Canine Adipose Tissue-Derived Stromal Cell Growth Characteristics

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Adipose-Derived Stem Cells

Part of the book series: Methods in Molecular Biology ((MIMB,volume 702))

Abstract

Stromal cells are undifferentiated cells found in embryonic and adult tissues. Adult mesenchymal stromal cells (MSCs) possess the properties of self renewal, long-term viability, multipotentiality, and immune privilege, which make them attractive candidates for regenerative medicine applications. In order to develop targeted adult stromal cell therapies for diseased and injured tissues in animals and humans, it is essential to have large-animal models. The dog represents not only a patient population, but is also a valuable experimental model. The dog has contributed significantly to the understanding of various human diseases such as genetic and musculoskeletal disorders. In order to optimize the use of stromal cell therapy in the dog as a patient or disease model, a comprehensive characterization of the cells is required.

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Acknowledgments

The author thanks the members of the Laboratory for Equine and Comparative Orthopedic Research at Louisiana State University, School of Veterinary Medicine for their advice and technical assistance. This project was funded by the National Institutes of Health Institute of Arthritis and Musculoskeletal and Skin Disease Grant #K01-AR002174.

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Authors and Affiliations

  1. Laboratory for Equine and Comparative Orthopedic Research, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA, USA

    Nakia D. Spencer & Mandi J. Lopez

Authors
  1. Nakia D. Spencer
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  2. Mandi J. Lopez
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Editor information

Editors and Affiliations

  1. , Stem Cell Biology, Pennington Biomedical Research Center, Perkins Rd. 6400, Baton Rouge, 70808, Louisiana, USA

    Jeffrey M. Gimble

  2. School of Medicine, Department of Pharmacology, Tulane University, Tulane Ave. 1430, New Orleans, 70112-2699, Louisiana, USA

    Bruce A. Bunnell

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Spencer, N.D., Lopez, M.J. (2011). In Vitro Adult Canine Adipose Tissue-Derived Stromal Cell Growth Characteristics. In: Gimble, J., Bunnell, B. (eds) Adipose-Derived Stem Cells. Methods in Molecular Biology, vol 702. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-61737-960-4_5

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  • DOI: https://doi.org/10.1007/978-1-61737-960-4_5

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  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-61737-959-8

  • Online ISBN: 978-1-61737-960-4

  • eBook Packages: Springer Protocols

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