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Identification of Promoter Regions and Regulatory Sites

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Computational Biology of Transcription Factor Binding

Part of the book series: Methods in Molecular Biology ((MIMB,volume 674))

Abstract

Promoter sequences are the main regulatory elements of gene expression. Their recognition by computer algorithms is fundamental for understanding gene expression patterns, cell specificity and development. This chapter describes the advanced approaches to identify promoters in animal, plant and bacterial sequences. Also, we discuss an approach to identify statistically significant regulatory motifs in genomic sequences.

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Authors and Affiliations

  1. Department of Computer Science, Royal Holloway, London, UK

    Victor V. Solovyev

  2. Bioinformatics Laboratory, Institute of Botany, ANAS, Baku, Azerbaijan

    Ilham A. Shahmuradov

  3. DOE Joint Genome Institute, Walnut Creek, CA, USA

    Asaf A. Salamov

Authors
  1. Victor V. Solovyev
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  2. Ilham A. Shahmuradov
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  3. Asaf A. Salamov
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Editors and Affiliations

  1. , Department of Statistics, University of Nebraska-Lincoln, Vine Street 1901, Lincoln, 68588-0665, Nebraska, USA

    Istvan Ladunga

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Solovyev, V.V., Shahmuradov, I.A., Salamov, A.A. (2010). Identification of Promoter Regions and Regulatory Sites. In: Ladunga, I. (eds) Computational Biology of Transcription Factor Binding. Methods in Molecular Biology, vol 674. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-60761-854-6_5

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  • DOI: https://doi.org/10.1007/978-1-60761-854-6_5

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