Piezoelectric Quartz Crystal Resonators Applied for Immunosensing and Affinity Interaction Studies

  • Petr Skládal
Part of the Methods in Molecular Biology™ book series (MIMB, volume 504)


Piezoelectric quartz crystals serve as resonator-based transducers for direct and real-time monitoring of immunoaffinity interactions. The measuring system is briefly characterized; several examples for immobilization of antibodies are recommended. The piezoelectric immunoassays employing direct, competitive, and displacement-based formats are demonstrated on examples. The method for kinetic characterization of immunoaffinity interactions is presented.

Key words

Immunosensor Biosensor Flow through immunoassay Biointeraction analysis 


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Copyright information

© Springer Science+Business Media, LLC 2009

Authors and Affiliations

  • Petr Skládal
    • 1
  1. 1.Department of BiochemistryMasaryk UniversityBrnoCzech Republic

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