What Statisticians Should Know About Microarray Gene Expression Technology

  • Stephen WelleEmail author
Part of the Methods in Molecular Biology book series (MIMB, volume 972)


This chapter briefly reviews how laboratories generate microarray data. This information may give data analysts a better appreciation of the technical sources of variability in the data and the importance of minimizing such variability by normalization methods or exclusion of aberrant arrays.

Key words

DNA arrays cDNAs RNAs rRNAs mRNAs hybridization Target quantitation Basic data processing 


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Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  1. 1.Functional Genomics CenterUniversity of RochesterRochesterUSA

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